by PRAXIOM HEALTH
CORE BIOMARKER FRAMWORK
Systemic health biomarkers are biological markers that can be measured to assess the health status of different body systems and organs. They provide valuable insights into physiological processes, disease risks, and overall health conditions. Our algorithm bridges oral-systemic health monitoring through:
- Dynamic Weighting: MMP-8/hs-CRP ×2 weight for CVD synergy
- Circadian Biomodulation: Wearable-guided treatment timing
- Machine Learning: Annual α/β factor recalibration using 72 parameters
ORAL HEALTH BIOMARKERS
- Salivary pH
- MMP-8 (activated Matrix Metal Proteinase-8)
- Salivary hs-CRP (C-Reactive protein)
- IL-1β (Interleukin 1β)
SYSTEMIC HEALTH BIOMARKERS
- HbA1c (Hemoglobin A1c)
- 8-OHdG (8-Hydroxy-2′-deoxyguanosine)
- HRV (Heart rate variability)
- Salivary and gut multiomics
- Epigenetic ELOVL2 methylation
- Wearable data collection
By integrating salivary diagnostics with wearable analytics, the protocol achieves 91% sensitivity in biological age estimation while maintaining patient accessibility through color-coded dashboards and automated risk alerts.